Late in 2025, the Organization of Economic Development Cooperation and Development (OECD) published a Guidance Document on the Generation, Reporting and Use of Research Data for Regulatory Assessment that aims to enhance consideration and use of research data for regulatory hazard identification and risk assessments for chemicals. The guidance aims to bridge the gap between the increasing amount of non-standard research data and the need for robust scientific data to inform regulatory assessments. This webinar will present a case study that operationalizes recommended data quality criteria to assess the regulatory relevance and reliability of in vitro and in vivo research data generated to inform endocrine assessments in the European regulatory context and beyond.