Welcome to the SETAC Pharmaceutical Interest Group (IG). To joint this IG, make sure you are signed in to your SETAC account then click "Join Group” near the top of this page.
Mission and Purpose
The Pharmaceuticals IG exists to serve as a scientific resource to all stakeholders impacted by the topic of pharmaceuticals in the environment, and fulfils the following mission and purpose:
- Serve as a focal point within SETAC as a means of involving the membership in research and discussions
- Stimulate critical assessment in order to establish the best available science
- Encourage the worldwide incorporation of the best available science and strategic approaches
- Advance the overall understanding of the fate, effects, and potential environmental consequences of pharmaceuticals
- Provide scientific support to ensure effective regulatory decision making
- Provide a neutral platform and focal point for collaborative identification, evaluation, and resolution of scientific issues
The scope of the SETAC Pharmaceuticals IG is human and veterinary pharmaceuticals. Personal Care Products (PCP) and other emerging contaminants are not included since it is specifically pharmacological bioactivity that has called into question the adequacy of the existing environmental risk assessment science for pharmaceuticals. Scientific coverage of the Pharmaceuticals IG includes all fields pertinent to conducting effective environmental risk assessments for pharmaceuticals, such as transport, fate, exposure, effect, and impact analysis. All environmental compartments, such as aquatic, terrestrial, and biomass are included.
The presence and potential hazards of pharmaceuticals in the environment have received increasing international attention in the academic and popular press, as well as within the regulatory community. This focus on the potential ecological effects from pharmaceuticals largely began as a result of a growing number of technical papers published from the late 1990s until the present that have reported the detection of low levels of pharmaceuticals in wastewater treatment plant effluent, manufacturing plant effluent and surface water and, to a more limited extent, groundwater, drinking water, soils, and sediment.
Environmental concerns about pharmaceuticals have consistently been linked to two factors:
- The bioactive properties of pharmaceuticals, which is the basis of their therapeutic (pharmacological) activity.
- The potential for pharmaceuticals to be continuously present, albeit at low concentrations, due to ongoing use.
Concerns have been raised about whether the current environmental risk assessment scientific methodology may need to be revised or replaced to evaluate the potential environmental impact of pharmaceuticals appropriately.
The Pharmaceuticals Interest Group (IG) was established to advance the science and understanding of pharmaceuticals in the environment in October 2005.
The Pharmaceuticals IG will develop and implement a long-range strategic plan for stimulating and participating in the advancement of Pharmaceuticals-related environmental science. Roles and responsibilities focus on identification of research needs and fostering scientific exchange. In specific, the steps the Pharmaceuticals IG may take to meet its mission and purpose include, but are not necessarily limited to:
- Preparation of technical papers (general information, issue specific)
- Developing a specific area of the SETAC web site for the Pharmaceuticals IG
- Developing a discussion forum on the SETAC web site
- Sponsoring general pharmaceuticals technical sessions at meetings
- Holding targeted (subject specific) discussion groups at meetings
- Implementing short courses, for example in advance of either SETAC or other conferences
- Communication of updates in the SETAC Globe
Pharmaceutical research highlight: Environmental Toxicology and Chemistry recently published articles
pH‐Dependent uptake and sublethal effects of antihistamines in zebrafish (Danio rerio) embryos
Lisa Bittner, Elisabet Teixidó, Isabel Keddi, Beate I. Escher, Nils Klüver
First Published: 19 February 2019
Advancing the Zebrafish embryo test for endocrine disruptor screening using micro‐injection: Ethinyl estradiol as a case study
Ellen D. G. Michiels, Lucia Vergauwen, Foon Yin Lai, Raewyn M. Town, Adrian Covaci, Alexander L. N. van Nuijs, Steven J. Van Cruchten, Dries Knapen
Pages: 533-547 | First Published: 20 December 2018
Overall approach of the present study to optimize and characterize the use of micro‐injection of lipophilic compounds into the yolk of zebrafish embryos for endocrine disruptor screening.
Evaluation of the subtle effects and oxidative stress response of chloramphenicol, thiamphenicol, and florfenicol in Daphnia magna
Zhang Yuxuan, Guo Peiyong, Wu Yanmei, Zhang Xiaoyan, Wang Meixian, Yang Simin, Sun Yinshi, Deng Jun, Su Haitao
Pages: 575-584 | First Published: 20 December 2018
Upcoming activities: SETAC Helsinki Special Session
The EU-IMI Project Intelligence-led Assessment of Pharmaceuticals in the Environment (iPiE)
Sunday 26 May, 13:00 – 17:30, Session Room 201
2018 Pharmaceuticals Interest Group Annual Report
2015 Pharmaceuticals Interest Group Annual Report
2014 Pharmaceuticals Interest Group Annual Report