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Seminal papers
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In the follow up of several discussions since the inception of the OMICS IF was identified the need for a list of seminal papers/resources which could be used both as an introduction to OMICS technologies and potential applications.

After a survey to the current members, some of the identified key reads are: 

Ø  A complete workflow for high-resolution spectral-stitching nanoelectrospray direct-infusion mass-spectrometry-based metabolomics and lipidomics (


Ø  A comprehensive assessment of RNA-seq accuracy, reproducibility and information content by the Sequencing Quality Control Consortium (


Ø  Differential gene transcription across the life cycle in Daphnia magna using a new all genome custom-made microarray (


Ø  Discovery of Metabolic Signatures for Predicting Whole Organism Toxicology (


Ø  Environmental metabolomics: a critical review and future perspectives (


Ø  Environmental metabolomics: Databases and tools for data analysis (


Ø  Environmental toxicology and omics: A question of sex (


Ø  Evolutionary Conservation of Human Drug Targets in Organisms used for Environmental Risk Assessments (


Ø  Gene Expression of Fathead Minnows (Pimephales promelas) Exposed to Two Types of Treated Municipal Wastewater Effluents (


Ø  How Omics Technologies can Enhance Chemical Safety Regulation: Perspectives from Academia, Government, and Industry (DOI: 10.1002/etc.4079)


Ø  Identification of Metabolic Pathways in Daphnia magna Explaining Hormetic Effects of Selective Serotonin Reuptake Inhibitors and 4-Nonylphenol Using Transcriptomic and Phenotypic Responses (


Ø  Incorporating Transgenerational Epigenetic Inheritance into Ecological Risk Assessment Frameworks (


Ø  Metabolic Profile Biomarkers of Metal Contamination in a Sentinel Terrestrial Species Are Applicable Across Multiple Sites (


Ø  Metabonomics in Toxicology: A Review (


Ø  Molecular toxicity of cerium oxide nanoparticles to the freshwater alga Chlamydomonas reinhardtii is associated with supra-environmental exposure concentrations (


Ø  NMR-Based Metabolomics: A Powerful Approach for Characterizing the Effects of Environmental Stressors on Organism Health (


Ø  Omics Advances in Ecotoxicology (DOI:10.1021/acs.est.7b06494)


Ø  Omics for aquatic ecotoxicology: Control of extraneous variability to enhance the analysis of environmental effects (


Ø  The genomic landscape of rapid repeated evolutionary adaptation to toxic pollution in wild fish (DOI: 10.1126/science.aah4993)


Ø  The Role of Epigenomics in Aquatic Toxicology (


Ø  The transcriptome-wide effects of exposure to a pyrethroid pesticide on the Critically Endangered delta smelt Hypomesus transpacificus (DOI:


Ø  Transcriptome profiling of developmental and xenobiotic responses in a keystone soil animal, the oligochaete annelid Lumbricus rubellus (


Ø  Transgenerational DNA Methylation Changes in Daphnia magna Exposed to Chronic γ Irradiation (


Ø  Tryptophan hydroxylase (TRH) loss of function mutations induce growth and behavioral defects in Daphnia magna  (


Ø  Understanding 'Global' Systems Biology: Metabonomics and the Continuum of Metabolism (


Ø  Use of Metabolomics to Advance Research on Environmental Exposures and the Human Exposome (


Ø  Using Gene Expression to Assess the Status of Fish from Anthropogenically Influenced Estuarine Wetland (


This list dos not intent, by any means, to be exhaustive and/or exclusive. Instead it stems from a community effort to educate the next generation of OMICs researchers.