In the follow up of several discussions since the inception of the OMICS IF was identified the need for a list of seminal papers/resources which could be used both as an introduction to OMICS technologies and potential applications.

After a survey to the current members, some of the identified key reads are: 

Ø  A complete workflow for high-resolution spectral-stitching nanoelectrospray direct-infusion mass-spectrometry-based metabolomics and lipidomics (https://doi.org/10.1038/nprot.2016.156)

Ø  A comprehensive assessment of RNA-seq accuracy, reproducibility and information content by the Sequencing Quality Control Consortium (https://doi.org/10.1038/nbt.2957)

Ø  Differential gene transcription across the life cycle in Daphnia magna using a new all genome custom-made microarray (https://doi.org/10.1186/s12864-018-4725-7)

Ø  Discovery of Metabolic Signatures for Predicting Whole Organism Toxicology (https://doi.org/10.1093/toxsci/kfq004)

Ø  Environmental metabolomics: a critical review and future perspectives (https://doi.org/10.1007/s11306-008-0152-0)

Ø  Environmental metabolomics: Databases and tools for data analysis (https://doi.org/10.1016/j.marchem.2015.06.012)

Ø  Environmental toxicology and omics: A question of sex (https://doi.org/10.1016/j.jprot.2017.09.010)

Ø  Evolutionary Conservation of Human Drug Targets in Organisms used for Environmental Risk Assessments (https://doi.org/10.1021/es8005173

Ø  Gene Expression of Fathead Minnows (Pimephales promelas) Exposed to Two Types of Treated Municipal Wastewater Effluents (dx.doi.org/10.1021/es401942n)

Ø  How Omics Technologies can Enhance Chemical Safety Regulation: Perspectives from Academia, Government, and Industry (DOI: 10.1002/etc.4079)

Ø  Identification of Metabolic Pathways in Daphnia magna Explaining Hormetic Effects of Selective Serotonin Reuptake Inhibitors and 4-Nonylphenol Using Transcriptomic and Phenotypic Responses (https://doi.org/10.1021/es4012299)

Ø  Incorporating Transgenerational Epigenetic Inheritance into Ecological Risk Assessment Frameworks (https://doi.org/10.1021/acs.est.7b01094)

Ø  Metabolic Profile Biomarkers of Metal Contamination in a Sentinel Terrestrial Species Are Applicable Across Multiple Sites (https://doi.org/10.1021/es0700303)

Ø  Metabonomics in Toxicology: A Review (https://doi.org/10.1093/toxsci/kfi102)

Ø  Molecular toxicity of cerium oxide nanoparticles to the freshwater alga Chlamydomonas reinhardtii is associated with supra-environmental exposure concentrations (https://doi.org/10.3109/17435390.2014.1002868)

Ø  NMR-Based Metabolomics: A Powerful Approach for Characterizing the Effects of Environmental Stressors on Organism Health (https://doi.org/10.1021/es034281x)

Ø  Omics Advances in Ecotoxicology (DOI:10.1021/acs.est.7b06494)

Ø  Omics for aquatic ecotoxicology: Control of extraneous variability to enhance the analysis of environmental effects (https://doi.org/10.1002/etc.3002)

Ø  The genomic landscape of rapid repeated evolutionary adaptation to toxic pollution in wild fish (DOI: 10.1126/science.aah4993)

Ø  The Role of Epigenomics in Aquatic Toxicology (https://doi.org/10.1002/etc.3930)

Ø  The transcriptome-wide effects of exposure to a pyrethroid pesticide on the Critically Endangered delta smelt Hypomesus transpacificus (DOI: https://doi.org/10.3354/esr00679)

Ø  Transcriptome profiling of developmental and xenobiotic responses in a keystone soil animal, the oligochaete annelid Lumbricus rubellus (https://doi.org/10.1186/1471-2164-9-266)

Ø  Transgenerational DNA Methylation Changes in Daphnia magna Exposed to Chronic γ Irradiation (https://doi.org/10.1021/acs.est.7b05695)

Ø  Tryptophan hydroxylase (TRH) loss of function mutations induce growth and behavioral defects in Daphnia magna  (https://doi.org/10.1038/s41598-018-19778-0)

Ø  Understanding 'Global' Systems Biology: Metabonomics and the Continuum of Metabolism (https://doi.org/10.1038/nrd1157)

Ø  Use of Metabolomics to Advance Research on Environmental Exposures and the Human Exposome (https://doi.org/10.17226/23414)

Ø  Using Gene Expression to Assess the Status of Fish from Anthropogenically Influenced Estuarine Wetland (dx.doi.org/10.1021/es2011308)

This list dos not intent, by any means, to be exhaustive and/or exclusive. Instead it stems from a community effort to educate the next generation of OMICs researchers.