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Global Interest Groups: Animal Alternatives

The mission of the Animal Alternatives in Environmental Science Interest Group is as follows:

  • Foster discussion of key technical challenges for the future of the 3Rs (reduction, refinement, and replacement of animal tests) in environmental science
  • Understand the state of the science in animal alternatives with respect to acute and chronic testing
  • Understand the landscape for future animal alternative needs
  • Develop the basis for collaborative progress by all stakeholders
  • Consider how animal alternatives in environmental science will impact risk assessment

Activities

The SETAC Europe Meeting in Helsinki is only a few days away and we wanted to remind you of the upcoming activities that are co-sponsored by your Global Animal Alternatives Interest Group:

 

Monday, May 27

 

10:50–15:30 | Session 1.02, Room 103          

Alternative Approaches to Animal Testing for Ecotoxicity Assessments: Exploring New And Novel Approaches

Co-chairs: Teresa J Norberg-King, Adam Lillicrap, Marta Sobanska, Scott E. Belanger

 

Posters MO 059 to MO 087, Exhibit Hall

Morning Coffee Break & Poster Viewing                  10:05 – 10:50

 Lunch Break & Poster Viewing                                  12:25 – 13:55

 Afternoon Coffee Break & Poster Viewing                15:30 – 16:15

 Poster Social & Poster Viewing                                  17:15 – 18:1

 

 17:00 – 18:00 | Session Room 103B 

Biannual meeting of the Global Animal Alternatives interest group meeting,  Come hear about:

o   Next Generation Tools for Ecological Toxicity Testing Challenge.  EPA is sponsoring a Federal Prize Competition, or Challenge, to incentivize development of low-cost transcriptomics platforms for four species of interest. We are seeking innovative companies, institutes, or individuals to develop commercially viable, low cost, high content, gene expression profiling assays for key test organisms.

o   HESI EnviroTox Database and tools that have been developed by HESI will be demonstrated.  Learn about a recent multi-sector, a global initiative on the ecological threshold of toxicological concern (EcoTTC) and take a look at the database and tools which include the PNEC calculation, Chemical toxicity distribution (CTD), and EcoTTC distribution.  The database and tools are freely available at www.envirotdatabase.org, and a manuscript (Connors et al., 2019) was recently published in ET&C (Open Access).

o   Volunteer for Webinar with your title and time.  Second Wednesday of the month at 1 p.m. Eastern.

o   And more…

Session and poster session titles are below:

10:55     103 A | Alternative Approaches to Animal Testing for Ecotoxicity Assessments: Exploring New And Novel ApproachesTeresa Norberg-King, Adam Lillicrap, Marta Sobanska, Scott Belanger

075 | Setting the Baseline in In Vitro Bioassays | Beate Escher

076 | 076 | Performance of Three-Dimensional Rainbow Trout (Oncorhynchus mykiss) Hepatocyte Spheroids for Evaluating Biotransformation of Pyrene | Maria Hultman

077 | Integrated Alternative Approaches for Bioaccumulation and Toxicokinetics: From in Vitro Data to In Silico Models | Alessandro Sangion,

075 | Setting the Baseline in In Vitro Bioassays | Beate Escher

076 | Performance of Three-Dimensional Rainbow Trout (Oncorhynchus mykiss) Hepatocyte Spheroids for Evaluating Biotransformation of Pyrene | Maria Hultman

077 | Integrated Alternative Approaches for Bioaccumulation and Toxicokinetics: From in Vitro Data to In Silico Models | Alessandro Sangion

078 | Detoxification Capacity of Zebrafish (Danio rerio) Early Life Stages: Characterization of the Glutathione Conjugation Pathway By Targeted Proteomics and Metabolite Analysis | Alena Tierbach,

079 | Developing in-Silico Predictions of Toxicity | Chrystalla Losif

080 | QSARs for Thiochemicals - A Case Study of Using Alternative Information for REACH Registrations | Monika Nendza

133 | EpiSuite Prediction Models: Suitable for Natural Toxins? | Inés Rodríguez Leal

134 | Use of time-Weighted Average Exposure Values in the Chronic Aquatic Risk Assessment | Magnus Wang

135 | EnviroTox Database: Overview and Applications | Michelle Embry

POSTERS

MO059 | Development of Short-Term Toxicity Test Methods to Estimate Chronic Toxicity using the Freshwater Parthenogenetic Mayfly, Neocloeon triangulifer | Teresa Norberg-King, U.S. Environmental Protection Agency, USA

MO060 | Development of Short-Term Toxicity Test Methods to Estimate Chronic Toxicity using the Freshwater Mussel (Fatmucket, Lampsilis siliquoidea) | Teresa Norberg-King, U.S. Environmental Protection Agency, USA

MO061 | A new network of in silico models to cope with REACH requirements for (Q)SAR and read-across: the LIFE CONCERT REACH project | Rodolfo Gonella Diaza

MO062 | Alternative approaches: how Firmenich has used the 3Rs to reduce the number of fish for REACH submissions | Sylvia Gimeno

MO063 | An MOA-consensus classification in the EnviroTox database | Aude Kienzler

MO064 | Application of Daphnia magna in toxicity assessment and detection of waterborne pathogens | Vu Quynh Anh Le

MO065 | Automated, high-throughput measurement of size and growth curves of small organisms in well plates | Roman Ashauer, University of York, UK

MO066 | Comparative toxicity of 20 nm Silver Nanoparticles (AgNP) and TiO2 Nanoparticles (TiO2NP) using CaCo2 cells | Edmund Pool, University of The Western Cape, South Africa

MO067 | Comparison of metabolism of fragrance chemicals in rainbow trout liver S9 sub-cellular fractions and in the invertebrate Hyalella azteca | Heike Laue, Givaudan Schweiz AG, Switzerland

MO068 | Developing an Integrated Approach to Testing and Assessment for Acute Fish Toxicity Testing | Christopher Fassbender

MO069 | Development of a rapid agar-based algae growth inhibition screening test | Ines Pimparel

MO070 | Dioxin and AhR impairs cardiac development via direct regulation of key mesoderm genes in human embryonic stem cells | Hualing Fu

MO071 | EcoToxChip: A toxicogenomics tool for chemical prioritization and environmental management | Nil Basu

MO072 | Effects of PCB 28, PCB 52 and PCB 118 on Primary Mantle and Gill Cell Cultures of Unio pictorum and Unio crassus | Pinar Arslan,

MO073 | Effects of Zinc Pyrithione and Copper Pyrithione on Primary Mussel Cell Cultures | Pinar Arslan

MO074 | Endocrine disruptors screening analyzing zebrafish sperm quality | Maitane Ipiñazar

MO075 | Enhancing the utility of the Sequence Alignment to Predict Across Species Susceptibility tool | Colin Finnegan

MO076 | Evaluation of skin mucus vitellogenin (VTG) in a Japanese Medaka fish sexual development test (OECD TG 234) with 17betaethinylestradiol (EE2) as contribution to 3Rs animal welfare concept | Sascha Pawlowski

MO077 | Extending International Guidance to Relevant Middle Eastern Organisms: Acute Exposure of 4 Aromatic Hydrocarbons to Indigenous Marine Species Using a Passive Dosing Approach | Josh Butler

MO078 | In vitro and in silico evaluation of antiproliferative activity and receptor binding affinity of newly synthesized succinimide derivatives | Maja Milanović

MO079 | In vitro test to detect the presence of neurotoxic compounds in water and sediment samples | Alma Sobrino-Figueroa

MO080 | Lipophilicity influence on estrogen binding affinity of newly synthesized succinimide derivatives | Natasa Milic

MO081 | Measuring oxidative stress in zebrafish cell lines via a novel in vitro assay | Sebastian Lungu, SLU Uppsala, Sweden

MO082 | Prediction of Acute Ecotoxicity of Chemical Substances by Graph Theory Approach | Bin-Le Lin

MO083 | Quality criteria for the development and application of (Q)SARs and further in silico methods in order to increase regulatory acceptance among various regulatory frameworks | Irini Julia Adaktylou,

MO084 | Skin sensitization assessment for agrochemicals - a suggested approach assessing the applicability of non-animal test methods/approaches and global acceptance | David Howes, Envigo Consulting Limited, United Kingdom

MO085 | Strategically Selecting Test Species using the Sequence Alignment to Predict Across Species Susceptibility (SeqAPASS) Tool | Jonathon Doering

MO086 | Toxicogenomic analysis of Akaki river water using Caenorhabditis elegans | Berhanu Sahilu, Addis

IG MO087 | SETAC Animal Alternatives in Environmental Science Interest Group | Teresa Norberg-King


Steering Team Members

 Adam Lillicrap                                   (Europe non-profit sector)

Teresa Norberg-King                          (US government sector)

Josh Butler                                          (US business sector)

Natalie Burden                                   (UK non-profit sector)

Scott Belanger                                    (US business sector)

Michelle Embry                                  (US NGO non-profit sector)

Marlies Halder                                    (Europe government sector)

Bob Hoke                                            (US business sector)

Sarah Hughes                                      (US business sector)

Lucy Lee                                             (Canada academia sector)

Marc Léonard                                     (Europe business sector)

Barnett Rattner                                   (US government sector)

Kristin Schirmer                                 (Europe academic sector)

Marta Sobanska                                  (Europe government sector)

 

 

Meeting Poster of the AAIG

aaes_2018_sacramento_poster.pdf

IG_Animal_Alternatives_MInne.pdf

 

 

Group Feed
Eziuche Amadike Ugbogu joined the group Global Interest Groups: Animal Alternatives.
Posted Thursday, July 11, 2019
Elizabeth Z. Lin joined the group Global Interest Groups: Animal Alternatives.
Posted Saturday, June 8, 2019
Stephan Baumann joined the group Global Interest Groups: Animal Alternatives.
Posted Friday, June 7, 2019
Monica Nowierski joined the group Global Interest Groups: Animal Alternatives.
Posted Thursday, June 6, 2019
Miguel Oliveira joined the group Global Interest Groups: Animal Alternatives.
Posted Wednesday, May 29, 2019
 More »

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Upcoming Events
SETAC Latin America 13th Biennial Meeting
Sunday, September 15, 2019

Chair
Teresa J. Norberg-King
Co-Chair
Adam Lillicrap

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