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Global Interest Groups: Endocrine Disrupter Testing and RA
Group Pages
Heiko L. Schoenfuss
Lisa A. Baumann


PhD position offer at University of Heidelberg: Thyroid regulation of eye development in zebrafish


Welcome to the SETAC Global Interest Group (IG) on Endocrine Disrupter Testing and Risk Assessment (EDTRA) webpage. Participation in the EDTRA IG is open to all interested parties. To become a member, make sure you are signed in to your SETAC account. Then click "Join Group” near the top of this page.

Mission and Scope

  • Serve as a neutral platform and a focal point within SETAC for collaborative research and discussion on the topic of endocrine disrupter testing and risk assessment
  • Have direct and active links with existing and relevant future SETAC interest groups (including, but not limited to the SETAC North America IG on Human Health Risk Assessment, the SETAC OMICS IG, and the SETAC Pharma IG)
  • Stimulate critical assessment and the development of strategic approaches using the best available science
  • Encourage the worldwide incorporation of the best available science and strategic approaches
  • Advance the overall understanding of the fate, effects and potential risk assessment consequences of known and suspected endocrine disrupters
  • Provide scientific support to ensure effective regulatory decision making
  • The scope of the EDTRA IG includes all fields pertinent to conducting effective testing and risk assessments of known or suspected endocrine disrupters such as transport, fate, exposure, effect and impact analysis. All environmental compartments are considered, as well as human health and ecosystem protection.

Planned Activities

  • Preparation of technical papers (general information, issue specific)
  • Developing a discussion forum on the SETAC web site
  • Sponsoring general endocrine disrupter testing and risk assessment technical sessions at meetings
  • Holding targeted (subject-specific) discussion groups at meetings
  • Implementing short courses, for example in advance of either SETAC or other conferences
  • Presentations to government agencies
  • Communication of updates in the SETAC Globe
  • Providing input to national and international test guideline development initiative
  • Providing educational materials for the public and school systems

Recent Activities


  • The SETAC EDTRA IG was established in 2012 to serve as a scientific resource to all stakeholders impacted by the topic of endocrine disruption in the environment. 
  • Since the 1990's, numerous research projects have focused on a wide range of chemicals that are known to interact with the endocrine systems of humans and wildlife.
  • Various natural and synthetic chemicals have been found to interfere with the endocrine systems of animals in laboratory studies, while field evidence indicates that endocrine systems of fish and other taxa can be impacted.
  • An environmental risk assessment approach is needed for endocrine disrupters, allowing optimal integration of exposure and effects information.
  • Our ability to conduct whole organism toxicity tests to understand chemical safety and specifically that of (potentially) endocrine disrupting substances has been outpaced by the synthesis of new chemicals for a wide variety of commercial applications (LaLone et al, 2017 DOI:10.1002/etc.3805).
  •  Scientists and risk assessors are turning to mechanistically-based studies to increase the efficiency of evaluation of these substances, making greater use of the available in vitro and in silico methods. In this context the Adverse Outcome Pathway (AOP) framework has gained traction in environmental endocrine regulatory science since it offers an effective and systematic means of capturing available knowledge describing linkages between mechanistic data and the apical toxicity endpoints required for regulatory assessments. 

Annual Reports

2017 EDTRA Annual Report 

2016 EDTRA Bi-annual Report

2015 EDTRA Annual Report 


Steering Committee (2017-2020 term)


Heiko Schoenfuss (Academic, North America) 



Lisa Bauman (Academic, Europe)


Anupama Kumar (Government, Asia-Pacific)

Diana Miguez (Government, Latin America)

Scott Lynn (Government, North America)


Katherine Coady (Business, North America)

Laurent Lagadic (Business, Europe)

Grace Panter (Business, Europe)

Chris Prosser (Business, North America)

Ellen Mihaich (Business, North America)

Tim Verslycke (Business, North America)


Past Steering Committee Members

Karen Kidd (University of New Brunswick , Canada)
Tom Hutchinson (Plymouth University, UK, - bio)
Taisen Iguchi (National Institute for Basic Biology, Japan)
Frank Mastrocco (Pfizer, Inc. , USA)
Henrik Holbech (University of Southern Denmark, Denmark)
Gary Ankley (U.S. EPA, USA - bio)
Thomas Backhaus (Sweden)
Chris Hickey (New Zealand)
Peter Matthiessen (Independent consultant, UK)
Lennart Weltje (BASF, Germany - bio)
Malyka Galay Burgos (ECETOC, Belgium)
Scott Dyer (USA)
Melanie Groos-Sorokin (Italy)
Betty Locey (USA)

Related Group News

Registration for SETAC Sacramento Is Now Open
Posted in Annual Meetings, Wednesday, July 11, 2018

Registration is now open for the SETAC North America 39th Annual Meeting, which will be held from 4-8 November in Sacramento, California. Please join us ... more »

 View All News »

Recent Forum Activity
Conference call 19th September 2018
Posted by: Maria Teresa P. Fagundes, Wednesday, September 19, 2018
Forum: Minutes conference calls and face to face meetings
2015 EDTRA AG annual report
Posted by: Roel Evens, Monday, November 2, 2015
Forum: Annual reports
2013 EDTRA AG annual report
Posted by: Roel Evens, Monday, November 2, 2015
Forum: Annual reports
2012 EDTRA AG annual report
Posted by: Roel Evens, Monday, November 2, 2015
Forum: Annual reports
ED Pellston Proposal - September 2015 revision_version II
Posted by: Roel Evens, Wednesday, September 23, 2015
Forum: ED Pellston Proposal
 View All Forums »

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