In the past decade, there has been a great deal of research on the environmental effects of pharmaceuticals and personal care products—also known as PPCPs—such as medicines, shampoo, and makeup. However, to date there has been no integrated publication of recent data on the fate and effects of these contaminants of emerging concern. A special issue of Environmental Toxicology and Chemistry focuses on how these substances degrade and travel through water, soil, and ecosystems and suggests how they should be assessed and managed. “This special issue … includes a timely collection of manuscripts examining the environmental chemistry, toxicology, risk assessment, and management of PPCPs,” write Bryan W. Brooks, Duane B. Huggett, and Alistair B.A. Boxall in the introductory editorial. The issue includes recent studies that have explored exposure and transportation of both human PPCPs and veterinary medicines in biosolids, soils, sediments, biota, and drinking water. Articles discuss the impacts of PPCPs on wildlife and water resource quality, as well as processes to remove PPCPs from aquatic environments. This research represents a broadening of the scope of the environmental concern that has traditionally focused on the impact of PPCPs on aquatic environments. It brings to light that pharmaceuticals released into soil could affect crops and that this foodborne exposure might be more significant than exposure through drinking water. Bryan W. Brooks, Associate Professor of Environmental Science and Biomedical Studies at Baylor University in Waco, Texas, served as the guest editor for the special issue. The entire special issue is available online with open access at http://www.setacjournals.org. Environmental Toxicology and Chemistry is a publication of the Society of Environmental Toxicology and Chemistry. It is interdisciplinary in scope and integrates the fields of environmental toxicology; environmental, analytical, and molecular chemistry; ecology; physiology; biochemistry; microbiology; genetics; genomics; environmental engineering; chemical, environmental, and biological modeling; epidemiology; and earth sciences. Emphasis is given to papers that enhance capabilities for the prediction, measurement, and assessment of the fate and effects of chemicals in the environment. For more information about the Society of Environmental Toxicology and Chemistry, please visit http://www.setac.org