Contents

List of Figures	xv
List of Tables	xvi
Foreword	xvii
Preface	xxv
Acknowledgments	xxvi
Abbreviations	xxvii
Chapter 1: Statement from the work session on chemically induced alternations in functional development and reproduction of fishes	3
Chapter 2: The TCDD toxicity equivalence approach for characterizing risks for early life-stage mortality in trout -Philip M. Cook, Erik W. Zabel, Richard E. Peterson	9
Chapter 3: Mechanisms of chemical interference with reproductive endocrine funtion in sciaenid fishes -Peter Thomas, Izhar A. Khan	29
Chapter 4: Environmental antiandrogens: potential effects on fish reproduction and development -Emily Monosson, William R. Kelce,, Michael Mac, L. Earl Gray	53
Chapter 5: Evidence for developmental and skeletal responses as potential signals of endocrine-disrupting compounds in fishes -William P. Davis	61
Chapter 6: Development of biomarkers for environmental contaminants affecting fish -Nancy D. Denslow, Marjorie Chow, Ming M. Chow, Sherman Bonomelli, Leroy C. Folmar, Scott A. Heppell, Craig V. Sullivan	73
Chapter 7: Assessment of estrogenic activity in fish -Alison C. Nimrod, William H. Benson	87
Chapter 8: Effect of pulp and paper mill contaminants on competence of rainbow trout macrophages -Isabelle Voccia, Jaime Sanchez-Dardon, Muriel Dunier, Stefan Chilmonczyk, Michel Fournier	101
Chapter 9: Reproductive and endocrine status of female kelp bass from a contaminated site in the Southern California Bight and estrogen receptor binding of DDTs -Robert B. Spies, Peter Thomas	113
Chapter 10: Early mortality syndrome in salmonid fishes from the Great Lakes -Susan V. Marcquenski, Scott B. Brown	135
Chapter 11: M74 syndrome: a review of potential etiological factors -Hans Borjeson, Leif Norrgren	153
Chapter 12: Laboratory and field observation of sublethal damage in marine fish larvae: lessons from the Exxon Valdez oil spill -Richard M. Kocan, Jo Ellen Hose	167
Chapter 13: Reproductive and developmental effects of contaminants in fish populations: establishing cause and effect -Emily Monosson	177
Abbreviations	351
Index	357